New Term Requests

[lschriml]

Requesting new ChEBI terms to describe drivers of disease, for the Disease Ontology project. The definitions were written for inclusion as environmental stressors in the ExO and ECTO exposure ontologies (@laurenechan).

polyfluoroalkyl substance - An endocrine disruptor that is polyfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm

perfluoroalkyl substance - An endocrine disruptor that is perfluoroalkyl substance, used widely in industrial applications, such as firefighting foams and non-stick pan, paper, and textile coatings. - https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm

ether glycol

• A chemical agent that is ether glycol.
• https://www.epa.gov/sites/production/files/2016-09/documents/glycol-ethers.pdf; https://www.cdc.gov/niosh/docs/83-112/default.html

brominated flame retardant - A fire retardant that is brominated flame retardant, contain bromine and are the most abundantly used flame retardants. Used in many consumer goods, including electronics, furniture, building materials, etc. and have been linked to endocrine disruption among other effects. - https://www.niehs.nih.gov/health/topics/agents/flame_retardants/index.cfm

heavy metal

• A poison that is a heavy metal, any metallic chemical element that has a relatively high density and is toxic or poisonous at low concentrations.
• https://www.lenntech.com/processes/heavy/heavy-metals/heavy-metals.htm#ixzz6s7SaXlej

Cheers, Lynn

[amalik01]

5 new ChEBI entries now created (I will try and add the child classes to these entries sometimes next week).

polyfluoroalkyl substance (CHEBI:172406) perfluoroalkyl substance (CHEBI:172397) glycol ether (CHEBI:172390) brominated flame retardant (CHEBI:172368) heavy metal (CHEBI:5631)

[lschriml]

Super !! Thank you !!

Cheers, Lynn

On Wed, May 12, 2021 at 5:00 AM amalik01 @.***> wrote:

5 new ChEBI entries now created (I will try and add the child classes to these entries sometimes next week).

polyfluoroalkyl substance (CHEBI:172406) perfluoroalkyl substance (CHEBI:172397) glycol ether (CHEBI:172390) brominated flame retardant (CHEBI:172368) heavy metal (CHEBI:5631)

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-- Lynn M. Schriml, Ph.D. Associate Professor

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[K-r-ll]

Could be nice to add these references too:

PMID: 20614099 PMID: 14738271 PMID: 15016455 PMID: 31766104

I think the definintive reference should be this one:

Duffus, J.H. (2002) "Heavy metals" a meaningless term? (IUPAC Technical Report) Pure and Applied Chemistry Vol. 74, Issue 5, 793-807. https://doi.org/10.1351/pac200274050793

HoweverI can't find its PMID