Incorrect resolution.
Games with the use of dxvk take the resolution from the second monitor (which is labeled 1) if you select the function windows show only the second monitor, then all okay I can take the resolution I need.
We've had a bunch of people reporting issues on Windows with games either starting on the wrong monitor or using settings of the wrong monitor.
Unfortunately we've never been able to reproduce any of it.
Are you using a laptop with an external screen or something like that?
No, just a PC and two monitors.
I kind of found a solution to just disable the monitor before startup, but it's very inconvenient.