pyBigWig

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addHeader does not support multiple calls

1

Not sure if this is intended or not but running `addHeader` multiple times seems to overwrite the existing header? Example ```python3 import pyBigWig with pyBigWig.open("example.bw", "w") as bw: header=[("chr1", 1000000),...

rlowe-altoslabs

This is because NonType is not iterable and `pyBigWig` cannot be used in loops right now

balwierz

Out of memory listing entries on one human chromosome on a machine with 300 GB ram and 165 GB BigBed file

1

I thought I could use this library for querying extremely large BigWig files, but despite providing python with 300 GB of ram it crashes anyway. Is pyBigWig keeping all the...

balwierz

this is my code: import pyBigWig bigwig_file = "MB12_H3K27me3copy.bw" bw = pyBigWig.open(bigwig_file, 'w') bw.addEntries(['chr3'], [103385937],ends=[103385938], values=[0.]) bw.close() When I run it I don't know why but I get this error:...

violacimatti

As initially identified in [Debian bug #1075407], pyBigWig fails to build with gcc 14 with the following relevant output: pyBigWig.c:773:12: warning: return discards ‘const’ qualifier from pointer target type [-Wdiscarded-qualifiers]...

emollier