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Suggestion - Zscore transformation a la hicFindTADs

Open samuelCollombet opened this issue 6 years ago • 1 comments

Hi, I find the Z-score transformation performed by hicFindTADs very useful for quantitative analysis of contact enrichment. I think it would be nice to add this way of transforming the matrix hicTransform as an "empirical Zscore" (on our data, the "obs_exp" transformation is very crude).

it is still possible to just get it by running hicFindTADs. However to run the conversion on a very large band around the diagonal, the subsequent parts of hicFindTADs take a lot of time (and is the only part really using the multi threading I think).

samuelCollombet avatar Dec 04 '18 16:12 samuelCollombet

Hi,

I think we can add this feature for release 2.3.

Best,

Joachim

joachimwolff avatar Dec 04 '18 17:12 joachimwolff