deepbiologic icon indicating copy to clipboard operation
deepbiologic copied to clipboard

Variable Domain Modeling

Open rbharath opened this issue 8 years ago • 1 comments

http://onlinelibrary.wiley.com/doi/10.1002/prot.24756/full

Would be worth reimplementing, but looks like data uses proprietary dataset.

rbharath avatar Jul 20 '17 01:07 rbharath

I agree with @rbharath —the methods used for Variable Domain Modeling in this paper are definitely worth investigating and re-implementing.

Since the original training data is proprietary, we should focus on extracting the key physicochemical features and the model architecture described. We can then train and benchmark the re-implemented model using the PNAS dataset (from Issue #7) as our gold standard for clinical-stage developability risks.

ChinmayRout9040895625 avatar Oct 25 '25 05:10 ChinmayRout9040895625