David S. Fischer

Hi @faniafeby, could you post the unique rows of your sample description? ie `adata_lcpm_1.obs[["time_point", "sample"]].drop_dupicates()`? Likely there is confounding between time and sample.

Yes, you have to think about what you want to model - the time effect or the time effect while reducing the between sample variance. if you want to do...

you can just add the `rep` col into the .obs, you dont have to recreate it!

Thanks @hramadas for the great debugging info, I will take care of this!

Hi @hramadas! All issues regarding xarray and xarray_sparse are now settled in the version on pypi and on github! Let me know if you encounter further problems!

Thanks @ivirshup! Which unit test did not work for you?

a couple of them are failing because there is paths in there specific to my machine because i need file IO for those tests, i have only been running the...

Hi @aopisco, thanks for reporting the issue! I am about to roll out a new version of the backend (batchglm), latest first week of January, this will also fix some...

@aopisco, I haven't forgotten this, I am finishing the new release of batchglm first and will address this in the new release of diffxpy after that.

@aopisco You could now again use the inital test z-test with nb noise, this should be fast/normal speed with the new optimizers. I will next look into the issue with...