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Published 20 hours ago • verified publisher icon cumc

Sample duplication issue in ROSMAP RNASeq and Genotype

Open hsun3163 opened this issue 2 years ago • 3 comments

This serves as a reminder of the Questions to be answered, @Rhopala will make a comprehensive description of the scenario later on. @gaow please correct me if I got the question wrong.

According to the ROSMAP metadata csv on synapse

  1. RNA Seq: 1.1. For some individual ID("R2809589"), there will be two records of RNA Seq for the same tissue. 1.1.1 why is that 1.1.2. how does it impact our analysis 1.1.3 what to do with it.

  2. Genotype 2.1 For some individual ID("R3257830"), there will be two records of WGS for the different or even same tissue ("R1631616"). 2.1.1 Why 2.1.2. how does it impact our analysis 2.1.3 The way to deal with it is by removing duplicates while maximizing overlap

hsun3163 avatar Sep 01 '22 17:09 hsun3163