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Norminal cis-windows for mQTL using TensorQTL

Open hsun3163 opened this issue 2 years ago • 5 comments

As noted in point 1 here: https://github.com/broadinstitute/tensorqtl/issues/68

there will be >400K CpG sites in the data compared to >20K genes. What would you suggest be a good cis_window for a CpG site, from a computational capacity perspective, for TensorQTL to analyze the data within reasonable CPU hours? 1Mbp radius may be too many tests?

Before this question got answered, this ticket will document some of the cis_windows other people use, although not necessarily using TensorQTL.

Cis_window is the number of bp up/downstream of the CpG site to determine what SNPs are to be included in the nominal association estimation.

hsun3163 avatar Jul 14 '22 19:07 hsun3163