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Published 20 hours ago • verified publisher icon csn-le

No Cluster 0

Open esbrady opened this issue 2 years ago • 3 comments

Hi Ferchaure,

I was just wondering, in instances where there is a cluster 1 but no cluster 0 (see below), does this mean that the detected units that would usually fall into cluster 0 have all grouped together to form cluster 1 instead? Is it likely that this cluster represents MUA/noise rather than SUA?

Screen Shot 2023-02-17 at 2 41 48 PM

Many thanks, Erica

esbrady avatar Feb 17 '23 22:02 esbrady

Hi Erica,

Technically cluster 0 are the spikes thar are too far away from the known templates and usually (not a real criterion) cluster 1 is the main clusters and MUA. In your case, everything is really similar to the single template found.

In my opinion: -Try with a positive threshold I saw a few positive peaks

  • That is MUA (or maybe just noise with a peak, try increasing a the detection threshold) and oddly fast for a neuron

ferchaure avatar Feb 18 '23 20:02 ferchaure

Thank you, Ferchaure! This is very helpful.

Other than noticing a large number of spikes that break the refractory limit, what are some other ways you can distinguish MUA from SUA in the wave_clus output?

esbrady avatar Feb 21 '23 20:02 esbrady

It's complicated a few MU criteria could be:

  • The smallest waveform not far away from the peak... far away neurons look the same (specially when the SNR is low).
  • Different levels of noise in some samples that gives you the idea that there are more than one waveform there.

ferchaure avatar Feb 22 '23 13:02 ferchaure