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RXN_AI, RXN_AM, and RXN_BOSS_FROM moved from SCDC to SCD/SBD

Open jrlegrand opened this issue 1 year ago • 0 comments

Problem Statement

RXN_AI was previously named RXN_BOSS_AI and attached to SCDC prior to September 2021 release. RXN_AM was previously named RXN_BOSS_AM and attached to SCDC prior to September 2021 release.

Now these are attached to SCD/SBD.

RXN_BOSS_FROM is derived from these as well and also now attached to SCD/SBD.

Need to figure out if we want to capture these and how they fit into the product data model.

Criteria for Success

TBD

Additional Information

https://www.nlm.nih.gov/research/umls/rxnorm/docs/appendix4.html

ATN Description ATV ATV Example(s)
RXN_AI† Attribute of Semantic Clinical Drug (SCD) or Semantic Branded Drug (SBD) atom referring to the active ingredient. The RXCUI of the SCDC responsible for the active ingredient value is also included in curly brackets as of September 2021.The Basis of Strength Substance (BoSS) is the active ingredient or active moiety in a drug product that is measured to provide the product strength.An active ingredient is any component that provides pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease, or to affect the structure or any function of the body of man or animals. RXCUI of active ingredient preceded by RXCUI of SCDC responsible for active ingredient value in curly brackets {329526} 104416{315951} 227224
RXN_AM‡ Attribute of SCD or SBD atom referring to the active moiety. The RXCUI of the SCDC responsible for the active moiety value is also included in curly brackets as of September 2021.An active moiety is the part of a drug that makes the drug work the way it does. More specifically, the active moiety is the molecule or ion, excluding portions of the molecule that cause the drug to be an ester, salt, or other noncovalent derivative of the molecule, responsible for the physiological or pharmacological action of the drug substance. RXCUI of active moiety preceded by RXCUI of SCDC responsible for active moiety value in curly brackets {1665355} 1191{315951} 4493
RXN_BOSS_FROM Attribute of SCD or SBD atom referring to the source of the BoSS as either from the active ingredient or the active moiety. The RXCUI of the SCDC responsible for the active ingredient (AI) or active moiety (AM) value is also included in curly brackets as of September 2021. “AI” or “AM" preceded by RXCUI of SCDC responsible for active ingredient or active moiety value in curly brackets {329526} AM

†Previously named RXN_BOSS_AI and attached to SCDC prior to September 2021 release. ‡Previously named RXN_BOSS_AM and attached to SCDC prior to September 2021 release.

jrlegrand avatar Sep 07 '22 16:09 jrlegrand