Other LoRa frequency bands

[Riconec]

I have LoRa radios for the 433 MHz and from docs

169 MHz, 433 MHz (Asia), 868 MHz (Europe) and 915 MHz (North America)

So in theory 13th harmonics for 902MHz you got is weaker than let's say 7th harmonics to reach 433MHz (at ~500MHz pll clock), but I not completely understand how mixing work. Is there any limitation to generate new LUTs for different frequency regions?