Chris Wallace

This is an error returned by the susie_rss() function in the package susieR.

You can guesstimate what the beta and varbeta are given the Z score, MAF, and information about the trait variance. That is what coloc.abf does. However, it is not a...

If you can use z scores directly, then do that :) ⁣http://chr1swallace.github.io​ On 15 Apr 2021, 19:25, at 19:25, daria-nikanorova ***@***.***> wrote: >Thank you very much for your quick answer!...

how do you want to pass z scores, by p value? Working with z scores isn't an option anywhere else in coloc, so it seems strange to introduce it here.

Varbeta is the square of the standard error. https://chr1swallace.github.io ________________________________ From: Matiss ***@***.***> Sent: Wednesday, April 6, 2022 6:18:56 PM To: chr1swallace/coloc ***@***.***> Cc: Chris Wallace ***@***.***>; Comment ***@***.***> Subject:...

Hi, I'm currently on holiday, so can't test, but I think this is an issue with documentation. The coloc.detail function was removed, but coloc.abf() updated so that sensitivity() should work...

Mmm. I'm not sure. Will look at this when back at a computer https://chr1swallace.github.io ________________________________ From: zillurbmb51 ***@***.***> Sent: Thursday, April 14, 2022 2:11:24 PM To: chr1swallace/coloc ***@***.***> Cc: Chris...

would it be possible for you to share (subsets of) your data so I can find out why this happens?