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runsusie() error with convergence

Open jvalliere opened this issue 9 months ago • 1 comments

Hello, I was wondering why in the runsusie() function convergence must be necessary in order to continue forward with colocalization. I had been running susie with two phenotypes in a region with ~6000 variants, and one was not reaching convergence. When I run susie_rss() myself with the data, the call does not converge but I get credible sets, which I thought could still be used for coloc. I then used annotate_susie() to make it compatible for coloc, and it worked fine. Is there a reason coloc must ensure convergence? Thank you so much for your help!

jvalliere avatar May 08 '24 15:05 jvalliere