coloc icon indicating copy to clipboard operation
coloc copied to clipboard

Why is the PP.H4.abf result of res$summary different from the maximum PP.H4 in res$results?

Open dqq0404 opened this issue 10 months ago • 3 comments

Hi, The res$summary results I get are as follows: nsnps PP.H0.abf PP.H1.abf PP.H2.abf PP.H3.abf PP.H4.abf 2.863000e+03 4.089385e-20 6.817232e-18 2.355242e-04 3.830173e-02 9.614627e-01 But when I opened res$results, I found that the largest PP.H4 was only 1.808670e-01. What's the problem?

dqq0404 avatar Apr 12 '24 06:04 dqq0404

PP.H4 is explained here https://chr1swallace.github.io/coloc/articles/a03_enumeration.html does that help?

-- https://chr1swallace.github.io


From: dqq0404 @.> Sent: Friday, April 12, 2024 7:08:23 AM To: chr1swallace/coloc @.> Cc: Subscribed @.***> Subject: [chr1swallace/coloc] Why is the PP.H4.abf result of res$summary different from the maximum PP.H4 in res$results? (Issue #161)

Hi, The res$summary results I get are as follows: nsnps PP.H0.abf PP.H1.abf PP.H2.abf PP.H3.abf PP.H4.abf 2.863000e+03 4.089385e-20 6.817232e-18 2.355242e-04 3.830173e-02 9.614627e-01 But when I opened res$results, I found that the largest PP.H4 was only 1.808670e-01. What's the problem?

— Reply to this email directly, view it on GitHubhttps://github.com/chr1swallace/coloc/issues/161, or unsubscribehttps://github.com/notifications/unsubscribe-auth/AAQWR2EMAFL2NICVF7BGEE3Y4525PAVCNFSM6AAAAABGDRAY3KVHI2DSMVQWIX3LMV43ASLTON2WKOZSGIZTSMJVG44TQMI. You are receiving this because you are subscribed to this thread.Message ID: @.***>

chr1swallace avatar Apr 12 '24 06:04 chr1swallace

Thanks!! I probably understand, so this result is correct.

dqq0404 avatar Apr 12 '24 06:04 dqq0404

Hi, my PP.H4.abf is 0.877, and the max SNP.PP.H4 is 0.19. Can I use this SNP as the causal SNP?

dqq0404 avatar Jun 07 '24 08:06 dqq0404