Adding distance restraints

[amin-sagar]

Hello ADCP developers. Thanks for sharing this program. I am wondering if it is possible to approximately simulate cyclization by crosslinkers by adapting the disulfide bond potential. If I change 2.2 to a larger value in the range of what it's supposed to be when crosslinked by another molecule and alter the dihedral term appropriately, will it work? Or are there more fundamental issues at the level of CRANKITE that have to be dealt with? In general, is it possible to have external distance restraints between sets of atoms if such information is available? I would be really grateful for any suggestions. Best, Amin.