ggpicrust2
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pathway_annotation() long runtime, connecting to KEGG database
Question: Is there a, general, expected runtime for the KEGG database connection step of the pathway_annotation() command?
This is my first time using the package, and I am passing (what I think is) a relatively small number of features, 228, to the annotation step - yet it's been running at the "We are connecting to the KEGG database to get the latest results, please wait patiently." step for ~6 hours.
If this runtime is expected, would it be possible to download the annotations ourselves and pass them to the annotation() command locally?
Thanks for any help you can provide!