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TMB Tool Bug Fix

Open Rima-Waleed opened this issue 2 months ago • 0 comments

  • Issue 1: Samples marked WXS/WGS in the gene panel matrix file but do not exist in the sequenced case list -> TMB = 0.0 (should be NA)
  • Issue 2: Gene panel matrix file has value "NA" for panel ID -> KeyError

Fixes:

  • "NA" is an accepted value in the gene panel matrix file
  • Samples that exist in sequenced case list and have an "NA" in the gene panel matrix file will have TMB computed
  • Samples in the gene panel matrix file with any value (WXS/WGS) but not present in the sequenced case list are not sequenced and so get "NA" for TMB instead of 0

Rima-Waleed avatar Oct 08 '25 16:10 Rima-Waleed