entropy.empirical with default fixed bin size?

[cbio-astar]

Can you check for entropy whether we are using entropy.empirical with default fixed bin size? The bin size should not be fixed across all dataset, it has to follow Doan’s rule: http://msmbuilder.org/mdentropy/0.3.0/generated/mdentropy.core.binning.doanes_rule.html#mdentropy.core.binning.doanes_rule

The formula can be found in methods (Entropy analysis): https://www.nature.com/articles/srep07137