What is the difference between fate probability and ancestor probability?

[jma1991]

Sorry for the naive question, but what is the difference between fate probabilities and the ancestor probabilities derived from trajectories? I assume cells which show high fate probabilities for a particular cell set at a given time point should also show high ancestor probabilities under the trajectory calculated for the same cell set and time point?

[geoffschieb]

Fate probabilities go forward in time, but ancestor probabilities go backward.

On Mon, Jan 18, 2021 at 9:28 AM James Ashmore [email protected] wrote:

Sorry for the naive question, but what is the difference between fate probabilities and the ancestor probabilities derived from trajectories? I assume cells which show high fate probabilities for a particular cell set at a given time point should also show high ancestor probabilities under the trajectory calculated for the same cell set and time point?

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