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Update browser for gnomAD v4.1 (checklist)

Open ch-kr opened this issue 11 months ago • 0 comments

Ticket to track various v4.1 data loading / update requests

Loading requests:

  • [x] #1439 | (@phildarnowsky-broad) Update code parsing SV and CNV files to accommodate updates, including updated metrics order, updated genetic ancestry terms, update from using gender to sex karyotype and reload SV, CNVs
  • [x] (@rileyhgrant) Load demo with PCSK9 (see thread) to get feedback on new flags below
  • [x] (@rileyhgrant) Load demo that contains only new gene constraint results (HT path shared here; gs://gnomad/v4.1/constraint/metrics/gnomad.v4.1.constraint_metrics.ht)
  • [ ] #1463 | (@rileyhgrant, @nadeaujoshua) Reload short variant exome and genome data
  • [ ] #1443 | (@rileyhgrant) Update downloads page links to point to new data
  • [ ] (riley to merge PRs, work done by methods team -- thank you!) Apply changes to help pages; current PRs:
    • [ ] #1430 | HT help page -- Qin added a few minor edits due to the slightly tweaked joint freq HT schema
    • [x] #1433 | v4.0>v4.1 updates -- this PR has been approved and is ready to go (note that I added a minor update to the dataset selection page on Apr 4)
    • [x] #1456 | Exome capture regions
    • [x] #1465 | describe new joint freq stats
    • [ ] #1476 | Add new flags to flags help page (new PR)
  • [ ] #1448 (@phildarnowsky-broad)| Make non-ukbb a selectable subset

Updates:

  • [x] #1423 | (@rileyhgrant) Add new flag indicating when a variant was not called in any data type
  • [x] #1442 | (@rileyhgrant) Add new flag for variants with discrepant frequencies between the exomes and genomes
  • [ ] #1440 | (@rileyhgrant) Update stats page to include number of samples in the two of the v4.0 exomes subsets
  • [x] #1458 | (@rileyhgrant) Not necessarily v4.1, but update typos on stats page
  • [ ] (no issue) | (@rileyhgrant) Update stats page to include average number of SNVs per person (still being calculated) -- edit to add that this has been pushed to post-v4.1 (hoping to have shortly afterwards)
  • [ ] (no link yet) Release v4.1 blog post when v4.1 data are loaded (methods team to stage, review, and approve staged post; will add link to PR when it exists)

Feedback

  • [x] #1475 | (@rileyhgrant) ticket tracking feedback on v4.1 demo browser

Will add updates if I've missed anything and as we create links for some of the topics above!

Also including v4.1 release checklist

ch-kr avatar Mar 15 '24 15:03 ch-kr