gatk icon indicating copy to clipboard operation
gatk copied to clipboard

Test out the preview version of the next GKL (DO NOT MERGE)

Open droazen opened this issue 11 months ago • 15 comments

Test out the preview version of the GKL, containing the new native PDHMM.

The jar was build using Java 1.8 and contains AVX optimized binaries for Linux hosts and not optimized binaries for Mac (Intel CPUs)

Example code showing how to call into the PDHMM is here: https://github.com/Intel-HLS/GKL/blob/master/src/test/java/com/intel/gkl/pdhmm/IntelPDHMMUnitTest.java

droazen avatar Mar 04 '24 21:03 droazen

@jamesemery Here's the branch we discussed -- see my notes above.

droazen avatar Mar 04 '24 21:03 droazen

A command line that triggered the crash in our testing:

gatk HaplotypeCaller -R /cromwell_root/gcp-public-data--broad-references/hg38/v0/dragen_reference/Homo_sapiens_assembly38_masked.fasta -I gs://broad-dsde-methods-dragen/reprocessed_data_v3.7.5_masked/CH1_CHM13_WGS1/CH1_CHM13_WGS1.bam -L /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-ScatterIntervalList/glob-cb4648beeaff920acb03de7603c06f98/109scattered.interval_list -O CH1_CHM13_WGS1.vcf.gz --pileup-detection --pileup-detection-absolute-alt-depth 0 --pileup-detection-bad-read-tolerance 0.4 --pileup-detection-enable-indel-pileup-calling --pileup-detection-active-region-phred-threshold 3.0 --use-pdhmm -contamination 0.0 -G StandardAnnotation -G StandardHCAnnotation --dragen-mode --disable-spanning-event-genotyping --dragstr-params-path /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-DragstrAutoCalibration/CH1_CHM13_WGS1.bam.dragstr -GQB 10 -GQB 20 -GQB 30 -GQB 40 -GQB 50 -GQB 60 -GQB 70 -GQB 80 -GQB 90

--dragstr-params-path /cromwell_root/fc-971fd540-210c-4e5a-87ce-d3f8c91c7557/submissions/0586864c-d263-4797-89f1-b517e487ad2a/VariantCalling/b177671c-e96b-433e-824a-f9d641184e75/call-DragstrAutoCalibration/CH1_CHM13_WGS1.bam.dragstr is likely optional

-L is optional and any interval will likely work to reproduce the error.

jamesemery avatar Apr 03 '24 14:04 jamesemery

Github actions tests reported job failures from actions build 10011498561 Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10011498561.2 logs

gatk-bot avatar Jul 19 '24 17:07 gatk-bot

Github actions tests reported job failures from actions build 10012664149 Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10012664149.2 logs

gatk-bot avatar Jul 19 '24 19:07 gatk-bot

Github actions tests reported job failures from actions build 10063197705 Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063197705.2 logs

gatk-bot avatar Jul 23 '24 17:07 gatk-bot

Github actions tests reported job failures from actions build 10063916773 Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063916773.2 logs

gatk-bot avatar Jul 23 '24 18:07 gatk-bot

Github actions tests reported job failures from actions build 10063991760 Failures in the following jobs:

Test Type JDK Job ID Logs
variantcalling 17.0.6+10 10063991760.2 logs

gatk-bot avatar Jul 23 '24 18:07 gatk-bot

Github actions tests reported job failures from actions build 10078507648 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10078507648.10 logs
variantcalling 17.0.6+10 10078507648.2 logs

gatk-bot avatar Jul 24 '24 14:07 gatk-bot

Github actions tests reported job failures from actions build 10099458986 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099458986.10 logs
variantcalling 17.0.6+10 10099458986.2 logs

gatk-bot avatar Jul 25 '24 18:07 gatk-bot

Github actions tests reported job failures from actions build 10099827390 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099827390.10 logs
variantcalling 17.0.6+10 10099827390.2 logs

gatk-bot avatar Jul 25 '24 19:07 gatk-bot

Github actions tests reported job failures from actions build 10099861078 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10099861078.10 logs
variantcalling 17.0.6+10 10099861078.2 logs

gatk-bot avatar Jul 25 '24 19:07 gatk-bot

Github actions tests reported job failures from actions build 10114843161 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10114843161.10 logs
variantcalling 17.0.6+10 10114843161.2 logs

gatk-bot avatar Jul 26 '24 17:07 gatk-bot

Github actions tests reported job failures from actions build 10146103273 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10146103273.10 logs
variantcalling 17.0.6+10 10146103273.2 logs

gatk-bot avatar Jul 29 '24 14:07 gatk-bot

Github actions tests reported job failures from actions build 10306895203 Failures in the following jobs:

Test Type JDK Job ID Logs
cloud 17.0.6+10 10306895203.10 logs
unit 17.0.6+10 10306895203.12 logs
integration 17.0.6+10 10306895203.11 logs
unit 17.0.6+10 10306895203.1 logs
variantcalling 17.0.6+10 10306895203.2 logs
integration 17.0.6+10 10306895203.0 logs

gatk-bot avatar Aug 08 '24 17:08 gatk-bot