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Engine read caching.

Open cmnbroad opened this issue 7 years ago • 2 comments

Allow tools to opt-in for read caching (enabled in this PR for CNNScoreVariants and FilterAlignmentArtifacts) when issuing forward-only queries such as those used to query a ReadsContext for all reads backing each variant.

The cache matches the (sometimes surprising - see https://github.com/broadinstitute/gatk/issues/4901) results that are returned when caching is not used, specifically that an unmapped but placed read that is mated with a mapped read is only returned if the start position overlaps the interval query interval, whereas the mapped read is returned if any part of the read overlaps the query interval.

cmnbroad avatar Jun 15 '18 20:06 cmnbroad