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Preferred IRIs for Xref properties

Open ariutta opened this issue 8 years ago • 0 comments

@egonw and I were discussing preferred IRIs for Xref properties in BridgeDb, and we'd welcome input from other community members on this.

This webservice endpoint http://webservice.bridgedb.org/Human/attributes/En/ENSG00000139618 returns:

Description    BRCA2, DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101]
Symbol    BRCA2
Type    protein_coding
Chromosome    13

To describe that call, do these IRIs appear correct? description: http://purl.org/dc/terms/description type: http://www.w3.org/1999/02/22-rdf-syntax-ns#type chromosome: http://purl.obolibrary.org/obo/GO_0005694 identifier: http://purl.obolibrary.org/obo/IAO_0000577 symbol: http://semanticscience.org/resource/SIO_000105

Does Symbol refer to name, as in one of these IRIs? https://vocabularies.wikipathways.org/gpml#textlabel http://schema.org/name http://www.biopax.org/release/biopax-level3.owl#name http://www.biopax.org/release/biopax-level3.owl#displayName http://www.biopax.org/release/biopax-level3.owl#standardName

Or is it specific to a gene symbol, as in http://edamontology.org/data_1026 from the EDAM ontology?

Note that http://webservice.bridgedb.org/Human/attributes/Ce/CHEBI%3A29108 returns:

Symbol    calcium
Symbol    Ca(2+)
Symbol    calcium(2+)
Symbol    calcium, doubly charged positive ion
Symbol    Ca
Symbol    Calcium element

and http://webservice.bridgedb.org/Human/attributeSearch/calcium?attrName=Symbol returns:

C9J224	Uniprot-TrEMBL	Voltage-dependent L-type calcium channel subunit beta-4 (Fragment)
HMDB00464	HMDB	Calcium
Q9P0X4	Uniprot-TrEMBL	Voltage-dependent T-type calcium channel subunit alpha-1I
CHEBI:4496	ChEBI	Dibasic calcium phosphate dihydrate
CHEBI:9679	ChEBI	Tricalcium phosphate
Q86V35	Uniprot-TrEMBL	Calcium-binding protein 7
O00305	Uniprot-TrEMBL	Voltage-dependent L-type calcium channel subunit beta-4
CHEBI:3309	ChEBI	Calcium Gluconate
CHEBI:5010	ChEBI	Fenprofen calcium
B0QYI5	Uniprot-TrEMBL	EF-hand calcium-binding domain-containing protein 6
P57103	Uniprot-TrEMBL	Sodium/calcium exchanger 3
HMDB38053	HMDB	Calcium trimetaphosphate
CHEBI:3311	ChEBI	Calcium carbonate
E7DBM8	Uniprot-TrEMBL	Voltage-dependent L-type calcium channel subunit beta-4
CHEBI:4757	ChEBI	Edetate calcium disodium
E7EN11	Uniprot-TrEMBL	Voltage-dependent L-type calcium channel subunit beta-4
HMDB14471	HMDB	Calcium Gluceptate
Q5THR3	Uniprot-TrEMBL	EF-hand calcium-binding domain-containing protein 6
F2Z391	Uniprot-TrEMBL	Sodium/calcium exchanger 3

ariutta avatar Dec 14 '16 21:12 ariutta