myvariant.info icon indicating copy to clipboard operation
myvariant.info copied to clipboard

Evaluate and potentially switch to use ClinVar's new VCV xml dump file

Open newgene opened this issue 2 years ago • 1 comments

VCV (variation in ClinVar) is a new variant-centric XML schema. More at https://pubmed.ncbi.nlm.nih.gov/31777943

MyVariant.info current imports data from ClinVar's original ClinVarFullRelease_*.xml.gz XML files (based on old RCV schema - no VCV content) at https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/

The newer ClinVarVariationRelease_*.xml.gz XML files (based on VCV schema - includes all data in ClinVar) are at https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/clinvar_variation/

Some variant-level aggregated interpretation, review status and explanation may only be available in VCV file.

newgene avatar Jul 21 '21 16:07 newgene

+1. CIViC would be very keen to display ClinVar aggregated classifications from myvariant.info!

obigriffith avatar Jul 21 '21 21:07 obigriffith