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where does 'function_of' RO:0000079 belong in the model?

Open sierra-moxon opened this issue 3 years ago • 3 comments

  • [ ] Document how to make Gene->Biological Process triples (which predicate to use when).
  • [ ] Where should 'function_of' be mapped in the model

sierra-moxon avatar May 28 '21 17:05 sierra-moxon

from issue #692 I find the word choice still a bit confusing. Is "enables"/"enabled by" meant to be similar in meaning to RO:0000085 (has_function) and its inverse RO:0000079 (function_of)? It's still not clear how to model a flat/simple Gene/Protein <-> Biological Process association. Is it "enables"/"enabled by" (also used by Gene/Protein <-> MolecularActivity?), or is it "acts upstream of or within"?

sierra-moxon avatar May 28 '21 21:05 sierra-moxon

https://github.com/biolink/biolink-model/issues/670

sierra-moxon avatar May 28 '21 22:05 sierra-moxon

I believe that in GO annotations the default relation between a gene product and a biological process is involved in. It's the composition of enables o part_of. But acts upstream of or within is a more general superproperty of this.

balhoff avatar Jun 01 '21 17:06 balhoff