Add METPO prefix for microbial ecophysiological trait ontology

[Copilot]

Adds the METPO (Microbial Ecophysiological Trait and Phenotype Ontology) prefix to enable representation of microbe-medium growth relationships in knowledge graphs.

Changes

• Added METPO: 'https://w3id.org/metpo/' to prefixes section in biolink-model.yaml
• Positioned alphabetically between METANETX.REACTION and MESH

Context

METPO provides terms for microbial phenotypes and growth characteristics used in:

• Culture collection data integration (BacDive, DSMZ, ATCC)
• KGX-based ETL pipelines for microbial knowledge graphs
• Strain-medium relationship modeling (e.g., METPO:2000517 for "grows in" predicate)

The ontology is hosted at w3id.org and follows OBO Foundry principles.

Original prompt

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This section details on the original issue you should resolve

<issue_title>Add METPO prefix to Biolink Model prefixes</issue_title> <issue_description>## Summary

Request to add the METPO (Microbial Ecophysiological Trait and Phenotype Ontology) prefix to the Biolink Model prefixes section.

Prefix Definition

METPO: 'https://w3id.org/metpo/'

Justification

METPO provides ontology terms for microbial phenotypes and growth characteristics that are essential for knowledge graph representations of microbe-medium relationships. Key terms include:

• METPO:1004005 - growth medium (class)
• METPO:2000517 - grows in (object property, domain: microbe, range: growth medium)
• METPO:2000518 - does not grow in (object property)

These terms have defined domains and ranges that complement Biolink's representation of organisms and chemical entities.

Use Cases

• Representing strain-medium growth relationships in knowledge graphs (e.g., "Methylobacterium extorquens grows in MP medium")
• Integrating data from culture collections (BacDive, DSMZ, ATCC)
• KGX-based ETL pipelines for microbial knowledge graphs

Related Resources

• METPO repository: https://github.com/berkeleybop/metpo
• w3id.org namespace: https://w3id.org/metpo/
• Related project: cmm-ai-automation (Critical Mineral Metabolism AI)

Notes

METPO is developed at LBNL/Berkeley BOP and follows OBO Foundry principles. The ontology is hosted at w3id.org rather than purl.obolibrary.org.

🤖 Generated with Claude Code</issue_description>

Comments on the Issue (you are @copilot in this section)

• Fixes biolink/biolink-model#1666

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