Forcing motor movement seems to have an impact on the I2C connection.

[linw1995]

board: manta-m8p v2

## Z0 Stepper - Front Left on MOTOR3_A
[stepper_z]
step_pin: PB8
dir_pin: PB7
enable_pin: !PE0
# Rotation Distance for TR8x8 = 8, TR8x4 = 4, TR8x2 = 2
rotation_distance: 8    
microsteps: 128
endstop_pin: probe:z_virtual_endstop
##  Z-position of nozzle (in mm) to z-endstop trigger point relative to print surface (Z0)
##  (+) value = endstop above Z0, (-) value = endstop below
##  Increasing position_endstop brings nozzle closer to the bed
##  After you run Z_ENDSTOP_CALIBRATE, position_endstop will be stored at the very end of your config
## All builds use same Max Z
position_max: 250
position_min: -5
homing_speed: 8.0 # Leadscrews are slower than 2.4, 10 is a recommended max.
second_homing_speed: 3
homing_retract_dist: 3

##	Make sure to update below for your relevant driver (2208 or 2209)
[tmc2209 stepper_z]
uart_pin: PB9
interpolate: false
run_current: 0.9
sense_resistor: 0.110
stealthchop_threshold: 0

##	Z1 Stepper - Rear  on Motor6
[stepper_z1]
step_pin: PG9
dir_pin: PD7
enable_pin: !PG11 
# Rotation Distance for TR8x8 = 8, TR8x4 = 4, TR8x2 = 2
rotation_distance: 8  
microsteps: 128

##	Make sure to update below for your relevant driver (2208 or 2209)
[tmc2209 stepper_z1]
uart_pin: PG10
interpolate: false
run_current: 0.9
sense_resistor: 0.110
stealthchop_threshold: 0

##	Z2 Stepper - Front Right on Motor7
[stepper_z2]
step_pin: PD4
dir_pin: PD3
enable_pin: !PD6
# Rotation Distance for TR8x8 = 8, TR8x4 = 4, TR8x2 = 2
rotation_distance: 8  
microsteps: 128

##	Make sure to update below for your relevant driver (2208 or 2209)
[tmc2209 stepper_z2]
uart_pin: PD5
interpolate: false
run_current: 0.9
sense_resistor: 0.110
stealthchop_threshold: 0

[temperature_sensor 打印仓-Corner]
sensor_type: BME280 # BMP388
i2c_address: 119
i2c_software_scl_pin: PA8
i2c_software_sda_pin: PC9

After completing the printing of large part models, Klippy unexpectedly entered shutdown mode as I was moving the build plate away from the bed. Interestingly, this issue doesn't occur when printing smaller models.

Klippy changed state to shutdown
MCU 'mcu' shutdown: soft_i2c NACK