placement of D-Ala-D-ala as a Van ligase

[cmungall]

I'm a bit confused by

http://purl.obolibrary.org/obo/ARO_3003970

Non-van ligases that synthesize D-Ala-D-Ala, the default cell wall precursor that makes a cell vulnerable to glycopeptide antibiotics. Mutations in the ddl gene can cause the production of nonfunctional/inactivated D-Ala-D-Ala ligases, which can render bacteria glycopeptide dependent depending on the presence of vancomycin resistance clusters.

Isn't this is the default form, which doesn't confer resistance, and isn't a Van ligase?

[github-actions[bot]]

This issue is being automatically closed due to lack of activity for 30 days. While the CARD team does it's best to keep up, sometimes we are unable to do so. Please re-open this issue if you still need assistance.

[github-actions[bot]]

This issue is being automatically closed due to lack of activity for 30 days. While the CARD team does it's best to keep up, sometimes we are unable to do so. Please re-open this issue if you still need assistance.