arbor icon indicating copy to clipboard operation
arbor copied to clipboard

Arbor-compatible NMODL representation of AMPA, NMDA, and GABA synapses

Open noraabiakar opened this issue 4 years ago • 10 comments

Several variants of the synapses can be found here: https://github.com/dbbs-lab/dbbs-mod-collection/tree/master/dbbs_mod_collection/mod

  • AMPA_0
  • AMPA_granule
  • GABA_0
  • GABA_biexp
  • GABA_granule
  • NMDA_granule
  • NMDA_stellate.

These mechanisms employ the use of arrays and net_send. Both of these features are not supported by arbor or the modcc compiler. This is mostly a placeholder issue.

noraabiakar avatar Nov 16 '21 14:11 noraabiakar

Do we have users requesting these mechanisms?

schmitts avatar Nov 22 '21 07:11 schmitts

The arborio team has been requesting these mechanism. I will tag the issue.

noraabiakar avatar Nov 26 '21 12:11 noraabiakar

Meetings of minutes related to this top can be found here

noraabiakar avatar Feb 07 '22 11:02 noraabiakar

@boeschf will try to get hold of @noraabiakar to see what the status is, and where the code is, if any.

brenthuisman avatar May 10 '22 11:05 brenthuisman

Code is here: https://github.com/noraabiakar/synapses but we have no PR or assignee, yet.

thorstenhater avatar May 10 '22 11:05 thorstenhater

@noraabiakar would you still be interested in wrapping this up? A minimal PR would be OK!

brenthuisman avatar Aug 02 '22 11:08 brenthuisman

@Helveg Do you still need this? Are there other AMPA/NMDA/GABA nmodl that do work, e.g. from a modeldb or do you need these specific ones? If so, why? We can discuss offline.

brenthuisman avatar Aug 30 '22 08:08 brenthuisman

Yes, still a project requirement of arborio

Helveg avatar Aug 30 '22 09:08 Helveg

Is the requirement for these specific ones, or could other implementations of these mechs be used? At the dev meet, it was suggested there exist mechs doing e.g. AMPA that don't rely on currently unsupported NMODL. Is that an option?

brenthuisman avatar Sep 01 '22 08:09 brenthuisman