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spatial differential gene expression analysis example does NOT reproduce

Open MobiTobi opened this issue 1 year ago • 0 comments

Running the Full Analysis Example on the mouse olfactory bulb datasets leads to diverging sdea results compared to the docs. The signal is too spread out and the regions of non-significance are greatly-diminished compared to the expected result.

Expected result: SDEA from Tutorial

Result: SDEA with deflated non-significant regions

All other plots reproduce perfectly. Increasing the n_std parameter changes the size of the region of non-significance as expected, so the function works at least a bit.

How can I trouble-shoot the sdea analysis?

MobiTobi avatar Jul 24 '23 12:07 MobiTobi