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Simbda Anti-VM
A sample (sha256: 09858ae19ce96499a78dd1f2a304a29caa7a1c220869cb6ec245b8fb91470c7e) has been using those not-yet-supported techniques to detect an analysis system/vm:
RegOpenKeyExA on
These here are anti-spyware detections
SubKey => SOFTWARE\SUPERAntiSpyware.com SubKey => SOFTWARE\Classes\SUPERAntiSpywareContextMenuExt.SASCon.1 SubKey => SOFTWARE\SUPERAntiSpyware.com
(generic ?) Sandbox detection
SubKey => Software\Classes*\shell\sandbox SubKey => Software\Classes\Folder\shell\sandbox
Sandboxie
SubKey => SYSTEM\CurrentControlSet\Services\SbieDrv SubKey => SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\Sandboxie
API Spy http://download.cnet.com/APIS32-API-Spy/3000-2247_4-9923.html
SubKey => SOFTWARE\APIS32 SubKey => Software\Microsoft\Windows\CurrentVersion\Explorer\MenuOrder\Start Menu2\Programs\APIS32 SubKey => SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\APIS32
Debugger
SubKey => Software\Syser Soft
Debugger
SubKey => SYSTEM\CurrentControlSet\Services\SDbgMsg
MS Debugging tools
SubKey => Software\Microsoft\Windows\CurrentVersion\Explorer\MenuOrder\Start Menu2\Programs\Debugging Tools for Windows (x86)
DotNet Stuff
SubKey => SOFTWARE\Classes\PEBrowseDotNETProfiler.DotNETProfiler
Password sniffer
SubKey => Software\Win Sniffer SubKey => SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\Win Sniffer_is1
IM Tool for companies ?
SubKey => Software\B Labs\Bopup Observer SubKey => AppEvents\Schemes\Apps\Bopup Observer SubKey => SOFTWARE\B Labs\Bopup Observer
Cygwin
SubKey => SOFTWARE\Cygwin SubKey => SOFTWARE\Cygwin
Packet analyser
SubKey => SOFTWARE\ZxSniffer
Wireshark
SubKey => SOFTWARE\Microsoft\Windows\CurrentVersion\App Paths\wireshark.exe SubKey => SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\Wireshark
Network monitor
SubKey => Software\eEye Digital Security SubKey => SYSTEM\CurrentControlSet\Services\IRIS5 SubKey => Software\CommView