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Meaning of compareClusterResults

Open IrelCM opened this issue 10 months ago • 1 comments

Hello, I would like to know if there is a description of an enrichResult object which is the result of the enricher(). I'm looking information to understand GeneRatio and BgRatio results. Because R Documentation only describe how to use the function but there is no explanation for the result.

Best regards. Irelka

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IrelCM avatar Jan 15 '25 13:01 IrelCM

enricher performs a over-representation test. More info can be found here: https://yulab-smu.top/biomedical-knowledge-mining-book/enrichment-overview.html#ora-algorithm

GeneRatio refers to In_category mentioned in the example, and BgRatio to not_in_category, respectively.

This expressed in the enricher code can be found here https://github.com/YuLab-SMU/DOSE/blob/4bdf261db7e2d088ca588a564f1db5a85ba522b7/R/enricher_internal.R#L138-L145

guidohooiveld avatar Jan 17 '25 12:01 guidohooiveld