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Segmentation fault in cas.pp.align_sequences

Open peipp410 opened this issue 7 months ago • 0 comments

Hello! I encountered the following error

joblib.externals.loky.process_executor.TerminatedWorkerError: A worker process managed by the executor was unexpectedly terminated. This could be caused by a segmentation fault while calling the function or by an excessive memory usage causing the Operating System to kill the worker.

in cas.pp.align_sequences when setting the gap_extend_penalty as a float number less then 1. I noticed that in our experiment, the Cas9 will cut a long sequence(about 200-300bp). Therefore, I want the gap extend penalty to be smaller so that it will record the alleles on two distant cutting sites that would otherwise be omitted by local alignment.

peipp410 avatar Aug 01 '24 06:08 peipp410