Any way to speed up the calculation?

[Yun-Ching-Chen]

Hi,

I've tried to run Enigma trace norm for ~500 TCGA samples using my own scRNA data (15 cell types with ~ 10000 genes) as the reference (in the aggregated 10000x15 matrix but not the Seurat object). It has been running over 24 hrs. I wonder if there is any tip to speed up the calculation or if it is possible to make a multi-core version?

Thanks, YC