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Workflow of imputation, doublet detection and data integration

Open xhbkirby opened this issue 4 years ago • 0 comments

If I want to incorporate doubelt detection in my scRNA-seq workflow, should I perform imputation before or after detecting and removing doublets? A second question is if I need to integrate multiple datasets, can I still perform imputation on individual dataset and use the imputed output as input for integration? Thanks!

xhbkirby avatar Apr 12 '20 08:04 xhbkirby