User-defined pseudo-bulk samples?

[borshago]

Hi,

I have data with cells from various individuals representing two different groups, and I'm interested in comparing the same cell types between the groups. I would like to use the individuals as replicates when running DEXSeq for DTU. Is there an easy way to modify the existing code so that the pseudo-bulk samples correspond to all the cells of interest in the available individuals?

Best, Daniel