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Published 20 hours ago • verified publisher icon Teichlab

potential workflow for MultiMAP.Integration for cross species analysis

Open deevdevil88 opened this issue 1 year ago • 2 comments

Hi, I had a quick question in regards to using MultiMAP for cross species analysis, should I only have the 1:1 orthologues between the two species in each of the AnnData objects, or can i also have unshared features?

Best, Devika

deevdevil88 avatar Jul 25 '22 16:07 deevdevil88

That's a neat application of MultiMAP!

You're welcome to have unshared features as well, and use those to compute the single-species dataset reductions. The transcriptomics plus ATAC integration in the demo has some number of unique features for each modality.

ktpolanski avatar Jul 29 '22 06:07 ktpolanski

Great! We will try it with unshared features then. Thanks for getting back to me . Best, Devika

deevdevil88 avatar Jul 29 '22 07:07 deevdevil88