weight_matrix with n_nearest_neighbors and n_neighbors

[wyq977]

Hi, I am wondering why there are two parameters for nearest neighbours in weight matrix calculation.

https://github.com/StatBiomed/SpatialDM/blob/aa1762496437a45787314a27e88313bdec6287c0/spatialdm/main.py#L34

It seems to me that there is no need for both or am I missing sth?

Best

[leeyoyohku]

n_neighbors is for secreted (long-distance) signaling, while n_nearest_neighbors is for adjacent signaling (ECM or cell-cell contact).