RTXteam
strange subclass_of edge in KG2.8.1pre
From Kaiwen He (reported by Slack DM):
Hi @ramseyst ! I notice something weird from an entry in RTX-KG2 2.8.1:
MONDO:0008491---rdfs:subClassOf---None---None---None---MONDO:0005015---OBO:mondo.owl False MONDO:000501biolink:subclass_of subclass_of infores:mondo {} subclass_of rdfs:subClassOf MONDO:0008491 2023-02-20 21:03:32 GMT biolink:subclass_of MONDO:0008491 MONDO:0005015
For this edge, it claims that MONDO:0008491 "stiff-person syndrome" is a subclass of MONDO:0005015 "diabetes mellitus".
According to the description of stiff-person syndrome, it does not sound like a subtype of diabetes.
Stiff-man syndrome (SMS) is a rare neurological disorder comprising fluctuating trunk and limb stiffness, painful muscle spasms, task-specific phobia, an exaggerated startle response, and ankylosing deformities such as fixed lumbar hyperlordosis.
From this link, there is a tree showing the ontology of stiff-person syndrome , but diabetes mellitus is not one of the superclasses. [Also attached the screenshot of the tree below]
Could you please verify this edge? I ask because it is related to one of the issues from NCATSTranslator/Feedback: https://github.com/NCATSTranslator/Feedback/issues/519, given that progressive encephalomyelitis with rigidity and myoclonus is a subclass of stiff-person syndrome . Thank you for your time!
https://github.com/NCATSTranslator/Feedback/issues/519
Kaiwen confirms, they saw this edge in KG2.8.1pre (the pre-canonicalized graph).
On KG2.8.6pre I don't see this edge. I ran the query match (n {id:"MONDO:0008491"})-[r]->(m {id:"MONDO:0005015"}) return * and returned no results, as shown below.
No results were returned for the same query against 2.8.4pre also
@saramsey Is there another way I should investigate this?
In KG2.10.0c, the only edge between MONDO:0008491 and MONDO:0005015 is biolink:coexists_with. Closing this issue.