DeepHistone

DeepHistone is a deep learning method to discriminate whether a DNA fragment has modification of a certain histone marker, using DNA sequence and chromatin accessibility information.

Requirements

• python 2.7/3.6
• pytorch 0.4
• numpy
• pandas
• sk-learn

Installation

Download DeepHistone by:

git clone https://github.com/QijinYin/DeepHistone

Installation has been tested in a Linux platform with python 2.7/3.6 .

Instructions

1. data preprocessing
   demo dataset was generated and saved in npz format.
2. model training and estimating

python train.py

Citation

• Paper is in review.

License

This project is licensed under the MIT License - see the LICENSE.md file for details