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nPhase has no option to set max heterozygosity level

Open OmarOakheart opened this issue 2 years ago • 0 comments

Whenever someone wants to run nPhase on a very heterozygous, large genome and runs into memory issues/takes too long to run, I recommend subsampling the vcf down to a 0.5~1% heterozygosity level since nPhase will still perform well (and significantly faster). This is probably a pain for everyone and it would be good to include an option to set a maximum heterozygosity level so that the pipeline can do the subsampling it on its own.

OmarOakheart avatar Oct 02 '21 11:10 OmarOakheart