How to optimize the hyperparameter in proteinNPT training process

[Meron-TANG]

Hi there,

Could you provide more details about the training set? In the ProteinNPT paper, you mention optimizing the model's hyperparameters using validation dataset. However, in the ProteinGym benchmark dataset, there is only a 5-fold split for each assay. Could you clarify if you optimized the hyperparameters using the validation set from just one assay and then applied them to the others? If not, what validation approach did you use? If so, which assay's validation set did you use, and how did you split in that dataset?

Thank you