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What is CCF_std/CCF_CI_High value, how can I get it?

Open LiuXiaodong1 opened this issue 4 years ago • 3 comments

This package needs that value to identify clonal/subclonal mutations. I can calculate CCF use EstimateClonality, but what's the difference between CCF and CCF_std?

LiuXiaodong1 avatar Aug 13 '20 08:08 LiuXiaodong1

I have the same problem. I get CCF with TitanCNA which output CellularPrevalence but no CellularPrevalence_std. How can I get it?

Thank you.

qindan2008 avatar Jun 29 '21 07:06 qindan2008

I have the same question.

cocoMA2020 avatar Apr 16 '22 10:04 cocoMA2020

@qindan2008 @cocoMA2020 The CCF_std represents the mean standard deviation of the predicted CCF for each mutation. The definition of the clonal status of mutations will be more accurate to integrate estimated CCF and CCF_std. If CCF_std is not available, you can set it as 0 for simplicity.

Niinleslie avatar May 20 '22 07:05 Niinleslie