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Extension for Maple format: including insertions

Open corneliusroemer opened this issue 2 years ago • 1 comments

In order to allow lossless compression, insertions need to be included in the Maple format.

I could find this edge case specified in the preprint.

It's easy to do, one just needs to agree to a convention, e.g.

2134 ins ACGTT

for an insertion of ACGTT after (or before) nucleotide 2134.

Alternative: no need for magic word, one simply includes multiple letters instead of one (I think this would be akin to VCF). If 2134 is usually C, one would write:

2134 CACGTT

for an insertion of ACGTT after nucleotide 2134.

Would be good of you could include treatment of insertions in the preprint.

I think both proposals would work in principle. Both have advantages.

The first is a bit more explicit, the second doesn't require a magic word.

corneliusroemer avatar Apr 01 '22 18:04 corneliusroemer