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Pragmatically ealing with repeats and evolutionarily diverged regions

Open DCGenomics opened this issue 7 years ago • 0 comments

Eventually, possibly in another hackathon, BUD should have a state dependent magicBLAST parameter modifier, where:

the parameters are tightened in regions with > average # of reads (repeats are presumably a main driver of this)

the parameters are loosened in regions with < average # of reads (divergence is presumably a main driver of this)

DCGenomics avatar Oct 05 '17 18:10 DCGenomics