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Transcription Factor Binding Prediction from ATAC-seq and scATAC-seq with Deep Neural Networks

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Hi, While I was installing maxATAC with Conda `conda create -n maxatac -c bioconda python=3.9 samtools wget bedtools ucsc-bedgraphtobigwig pigz` `pip install maxatac` # Test installation `maxatac -h` I noticed...

Hi! I am trying to run maxATAC on `scATAC` data from 10X system. I am running `maxatac preapre` and pointing the function to my fragments file that ends with `.tsv.gz`...

Hi, I was wondering what I need to adjust and to which constants.py I need make the adjustment to change the location of reference data? I am working on a...

Removed certain flags (-n, --name) that do not yield expected behavior and added one flag (--tf) that can also specify TFs.

We have this conflict between tensorflow and shap, where tensorflow 2.5 cannot work with numpy >=1.20.0 and shap is compiled with numpy API version 0xe (numpy >=1.20.0 I believe, the...

bug

https://github.com/MiraldiLab/maxATAC/blob/83cd5d2b95037cb2b100f72c0545e244336de72c/maxatac/utilities/normalization_tools.py#L47 ```bash File "/gpfs/home/.conda/envs/maxatac/lib/python3.9/site-packages/maxatac/utilities/genome_tools.py", line 236, in chromosome_blacklist_mask return blacklist_bigwig_stream.values(chromosome, TypeError: values() takes no keyword arguments ``` Same format in another file: https://github.com/MiraldiLab/maxATAC/blob/83cd5d2b95037cb2b100f72c0545e244336de72c/maxatac/utilities/genome_tools.py#L239 Removing numpy=True seems to resolve the issue.

Hi Tareian, It's me again, after fixed prepare function on samtools and bedGraphToBigWig by reinstallation, the predict function got some "cannot open shared object file: No such file or directory"...

We currently only produce plots for `train` and `benchmark`. It would be nice to add some additional plotting functions. - [ ] Plot bar plot of max values across chromosomes...

enhancement

We want to test out which model parameters are best for predicting TF binding - [ ] Kernel size - [ ] Filter number - [ ] Receptive Field -...

enhancement
analysis