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What's the difference

Open haowBio opened this issue 2 years ago • 1 comments

hi ~ What's the difference between barcode hm match and barcode match.

haowBio avatar Mar 28 '22 02:03 haowBio

Hi, the match_cell_barcode binary file was outdated. barcode match should read fuzzy match. I added some description to match_cell_barcode here.

The “Barcode hm match” count includes both exact matches and matches within MAX_DIST hamming edit distances. MAX_DIST is the 5th argument for match_cell_barcode. Fuzzy matches are reads that are aligned to the flanking sequence (because barcodes could not be found within the expected region), and then matched to barcodes within MAX_DIST Levenshtein edit distances (allowing indel).

ChangqingW avatar Apr 03 '22 04:04 ChangqingW