Aaron Lun

Looks like an actual error but I can't diagnose it without my work laptop, so just skipped the test for the time being.

> Hi, when I use `multiBatchNorm` to do normalization and adjust for the sequencing depth, I tried to figure out it by changing the argument `min.mean`, but it cannot work....

I have no idea. I assume that `expr` is a matrix or `dgCMatrix`, and not some custom class that might be reinterpreted as a list.

Well, I dunno. Works fine for me on **batchelor** 1.10.0. ```r library(batchelor) x

Another simple fix would be to just update `hapmap_exome_chr22.vcf.gz` so that it doesn't have this non-compliant header. I only stumbled across this because I was rummaging around **VariantAnnotation**'s VCFs to...

Just ran into this problem, which is quite inconvenient. Some investigative work suggests that **VariantAnnotation** already has a lot of the machinery required to decompress and read Gzipped (but not...

Do we have a time-frame for this @mtmorgan? I can merge LTLA/csaw#4 as it is now, but performance in @jmacdon's use case is going to be pretty bad...

Indeed, I didn't even know about `relist` until a few days ago when I was poking around inside _IRanges_. My motivation for `unlist

I don't have any strong feelings either way. I could imagine that the inconsistency with base R might cause problems to someone, but a function would need to explicitly protect...

Some detective work indicates that this is caused by an auto-generated `coerce` method: ``` > selectMethod("coerce", c("MyExperiment", "SummarizedExperiment")) Method Definition: function (from, to = "SummarizedExperiment", strict = TRUE) if (strict)...