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vest and chasmplus: report FDR

Open joshua-gould opened this issue 5 years ago • 1 comments

In addition to reporting the p-value, can you also please output the FDR? Thanks.

joshua-gould avatar Feb 28 '20 15:02 joshua-gould

The current OpenCravat software architecture relies on fetching pre-computed annotations one variant at a time. FDR calculations depend on the entire user-submitted data in a run, so it cannot be pre-computed. However, we are currently working on incorporating FDR calculations computed “on the fly” for both VEST and CHASMplus.

rkimoakbioinformatics avatar Apr 02 '20 21:04 rkimoakbioinformatics