question on MTAG

[aihualin]

Hi, I'm working on MTAG to combine 4 traits. Inputs are trait_1.txt, trait_2.txt, trait_3.txt and trait_4.txt. Outputs are MTAG_trait_1.txt , MTAG_trait_2.txt, MTAG_trait_3.txt and MTAG_trait_4.txt.

I wonder if the snps in the output MTAG_trait_1.txt is expected to be a sub-list of the snps in the first input trait_1.txt?

And snps in MTAG_trait_2.txt is a sub-list of snps in trait_2.txt and so on?

Thanks a lot!

All the best, Aihua

[paturley]

Hello, Aihua!

It should be. One of the first steps of the MTAG program is to filter the SNPs down to the intersection of all the GWAS files.

Best, Patrick

On Wed, Mar 31, 2021 at 8:43 AM Aihua Lin @.***> wrote:

Hi, I'm working on MTAG to combine 4 traits. Inputs are trait_1.txt, trait_2.txt, trait_3.txt and trait_4.txt. Outputs are MTAG_trait_1.txt , MTAG_trait_2.txt, MTAG_trait_3.txt and MTAG_trait_4.txt.

I wonder if the snps in the output MTAG_trait_1.txt is expected to be a sub-list of the snps in the first input trait_1.txt?

And snps in MTAG_trait_2.txt is a sub-list of snps in trait_2.txt and so on?

Thanks a lot!

All the best, Aihua

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[aihualin]

Hi, Patrick,

Thanks!

All the best, Aihua